GIGYF2 localizations
GIGYF2 [ENSP00000387170]
GRB10-interacting GYF protein 2; Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation . In 4EHP-GYF2 the complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay (By similarity). May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors ; Belongs to the GIGYF family.
Synonyms: GIGYF2, GIGYF2p, hGIGYF2, A0A1U8QZH8, B8ZZD2 ...