PLEKHG2 localizations
PLEKHG2 [ENSP00000392906]
Pleckstrin homology domain-containing family G member 2; May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein) . Involved in the regulation of actin polymerization .
Synonyms: PLEKHG2, PLEKHG2p, hPLEKHG2, C9J7S4, C9JVL3 ...