COMPARTMENTS

Subcellular localization database

KAT8 localizations

KAT8 [ENSP00000406037]

Histone acetyltransferase KAT8; Histone acetyltransferase which may be involved in transcriptional activation . May influence the function of ATM . As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac (PubMed:16227571, PubMed:16543150, PubMed:21217699, PubMed:22547026, PubMed:22020126). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues . That activity is less specific than the one of the MSL complex . Can also acetylate TP53/p53 at 'Lys-120'. ECO:0000269|PubMed:16227571, ECO:0000269|PubMed:16543150, ECO:0000269|PubMed:20018852, ECO:0000269|PubMed:21217699,

Synonyms:  KAT8,  KAT8p,  hKAT8,  A0A494C0I2,  H3BMX5 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence