TDRD5 localizations
TDRD5 [ENSP00000406052]
Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).
Synonyms: TDRD5, TDRD5p, hTDRD5, A0A024R910, A0A0C4DG74 ...