TRIM26 localizations
TRIM26 [ENSP00000410446]
Tripartite motif-containing protein 26; E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1; Belongs to the TRIM/RBCC family.
Synonyms: TRIM26, TRIM26p, hTRIM26, A0A024RCP3, A2AE48 ...