FBLIM1 localizations
FBLIM1 [ENSP00000416387]
Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. ECO:0000269|PubMed:12679033, ECO:0000269|PubMed:18829455,
Synonyms: FBLIM1, FBLIM1p, hFBLIM1, D6R9I4, D6R9V9 ...