LARP7 localizations
LARP7 [ENSP00000422626]
La-related protein 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Synonyms: LARP7, LARP7p, hLARP7, D6R9Z6, D6RAF3 ...