TNFAIP8 localizations
TNFAIP8 [ENSP00000427424]
Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Synonyms: TNFAIP8, TNFAIP8p, hTNFAIP8, D6RCM8, E5RIJ3 ...