COMPARTMENTS

Subcellular localization database

MYBL1 localizations

MYBL1 [ENSP00000429633]

Myb-related protein A; Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' . Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity). Transcriptional activator of SOX30 (By similarity).

Synonyms:  MYBL1,  MYBL1p,  hMYBL1,  E7EWZ1,  P10243 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence