PPP4R3A localizations
PPP4R3A [ENSP00000450864]
Serine/threonine-protein phosphatase 4 regulatory subunit 3A; Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair. ; Belongs to the SMEK family.
Synonyms: PPP4R3A, PPP4R3Ap, hPPP4R3A, A0A024R6M2, G3V231 ...