GMPR2 localizations
GMPR2 [ENSP00000454038]
GMP reductase 2; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (PubMed:12009299, PubMed:12669231, PubMed:16359702, PubMed:22037469). Plays a role in modulating cellular differentiation . ECO:0000269|PubMed:12669231, ECO:0000269|PubMed:16359702,; Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Synonyms: GMPR2p, hGMPR2, A0A087WWM4, A0A0B4J281, F8WAN9 ...