MCRIP1 localizations
MCRIP1 [ENSP00000461433]
Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition .
Synonyms: MCRIP1, MCRIP1p, hMCRIP1, A0A024R8R5, C9JLW8 ...