UNK localizations
UNK [ENSP00000464893]
RING finger protein unkempt homolog; Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes . ; Belongs to the unkempt family.
Synonyms: UNK, A0A024R8N4, K7EIZ1, K7ELF5, K7EMB1 ...