COMPARTMENTS

Subcellular localization database

MAP4K1 localizations

MAP4K1 [ENSP00000465039]

Mitogen-activated protein kinase kinase kinase kinase 1; Serine/threonine-protein kinase, which may play a role in the response to environmental stress . Appears to act upstream of the JUN N-terminal pathway . May play a role in hematopoietic lineage decisions and growth regulation . Able to autophosphorylate . Together with CLNK, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity).

Synonyms:  MAP4K1,  MAP4K1p,  hMAP4K1,  K7EJS6,  K7EKT6 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence