SPC24 localizations
SPC24 [ENSP00000465075]
Kinetochore protein Spc24; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore . The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules .
Synonyms: SPC24, SPC24p, hSPC24, A0A0A0MSN0, K7EJH0 ...