COMPARTMENTS

Subcellular localization database

IER2 localizations

IER2 [ENSP00000465617]

Immediate early response gene 2 protein; DNA-binding protein that seems to act as a transcription factor . Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis . ECO:0000250|UniProtKB:Q6P7D3, ECO:0000269|PubMed:19584537,; Belongs to the IER family.

Synonyms:  IER2,  IER2p,  hIER2,  A0A024R7H1,  Q9BTL4 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence