WDR18 localizations
WDR18 [ENSP00000476117]
WD repeat-containing protein 18; Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes . Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit ; Belongs to the WD repeat IPI3/WDR18 family.
Synonyms: WDR18, WDR18p, hWDR18, A0A087X237, A0A0A0MQU0 ...