ABCB1 localizations
ABCB1 [ENSP00000478255]
ATP-dependent translocase ABCB1; Translocates drugs and phospholipids across the membrane . Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins . Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells .
Synonyms: ABCB1, ABCB1p, hABCB1, A4D1D2, E7EWT8 ...