GRIA3 localizations
GRIA3 [ENSP00000481554]
Glutamate receptor 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA3 subfamily.
Synonyms: GRIA3, GRIA3p, hGRIA3, A0A087WYJ6, P42263 ...