Subcellular localization database

STRADB localizations

STRADB [ENSP00000194530]

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).

Synonyms:  STRADB,  A0A024R420,  ALS2CR2,  ALS2CR2-001,  ALS2CR2-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence