COMPARTMENTS

Subcellular localization database

DNASE2 localizations

DNASE2 [ENSP00000222219]

Deoxyribonuclease II, lysosomal; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells; Belongs to the DNase II family.

Synonyms:  DNASE2,  DNASE2p,  hDNASE2,  A0A024R7F4,  B7Z4K6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence