COMPARTMENTS

Subcellular localization database

COTL1 localizations

COTL1 [ENSP00000262428]

Coactosin-like F-actin binding protein 1; Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.

Synonyms:  COTL1,  COTL1p,  hCOTL1,  COTL1-001,  COTL1-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence