Subcellular localization database

DBF4 localizations

DBF4 [ENSP00000265728]

DBF4-type zinc finger-containing protein 1; Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle; Zinc fingers DBF-type

Synonyms:  DBF4,  DBF4p,  hDBF4,  B3KMY2,  B4DXK0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence