SPG7 localizations
SPG7 [ENSP00000268704]
Spastic paraplegia 7 (pure and complicated autosomal recessive); ATP-dependent zinc metalloprotease. Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable for this function; In the N-terminal section; belongs to the AAA ATPase family.
Synonyms: SPG7, SPG7p, hSPG7, H3BMP1, H3BTY6 ...