Subcellular localization database

DISP1 localizations

DISP1 [ENSP00000284476]

Dispatched homolog 1 (Drosophila); Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal (By similarity). Synergizes with SCUBE2 to cause a increase in SHH secretion; Belongs to the dispatched family.

Synonyms:  DISP1,  DISP1p,  hDISP1,  Q96F81,  DISPA ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence