Transforming growth factor-beta-inducible early growth response protein 1; Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation; Belongs to the Sp1 C2H2-type zinc-finger protein family.
Synonyms: KLF10, KLF10p, hKLF10, Q13118, Q13118p ...