Subcellular localization database

TMIGD2 localizations

TMIGD2 [ENSP00000301272]

Transmembrane and immunoglobulin domain-containing protein 2; Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T- cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade; Immunoglobulin like domain containing

Synonyms:  TMIGD2,  TMIGD2p,  hTMIGD2,  Q96BF3,  CD28H ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence