COMPARTMENTS

Subcellular localization database

E4F1 localizations

E4F1 [ENSP00000301727]

Putative E3 ubiquitin-protein ligase E4F1; May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription; Zinc fingers C2H2-type

Synonyms:  E4F1,  E4F1p,  hE4F1,  H3BN24,  H3BSL4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence