Putative E3 ubiquitin-protein ligase E4F1; May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription; Zinc fingers C2H2-type
Synonyms: E4F1, E4F1p, hE4F1, H3BN24, H3BSL4 ...