COMPARTMENTS

Subcellular localization database

BCL2L1 localizations

BCL2L1 [ENSP00000302564]

Apoptosis regulator Bcl-X; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis; Belongs to the Bcl-2 family.

Synonyms:  BCL2L1,  BCL2L1p,  hBCL2L1,  Q07817,  Q5QP56 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence