COMPARTMENTS

Subcellular localization database

RFX2 localizations

RFX2 [ENSP00000306335]

Regulatory factor X, 2 (influences HLA class II expression); Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (By similarity). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis- specific histone gene HIST1H1T (By similarity).

Synonyms:  RFX2,  RFX2p,  hRFX2,  K7EIN5,  K7EJD4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence