COMPARTMENTS

Subcellular localization database

PPM1D localizations

PPM1D [ENSP00000306682]

Protein phosphatase magnesium-dependent 1 delta; Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation.

Synonyms:  PPM1D,  PPM1Dp,  hPPM1D,  B4DSJ4,  K7EJH1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence