COMPARTMENTS

Subcellular localization database

NECAB2 localizations

NECAB2 [ENSP00000307449]

N-terminal EF-hand calcium binding protein 2; May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation; EF-hand domain containing

Synonyms:  NECAB2,  NECAB2p,  hNECAB2,  H3BPH6,  H3BTW2 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence