COMPARTMENTS

Subcellular localization database

JensenLab

PINX1 localizations

PINX1 [ENSP00000318966]

PIN2/TERF1-interacting telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. ECO:0000269|PubMed:19117989, ECO:0000269|PubMed:19265708,; Belongs to the PINX1 family.

Synonyms:  PINX1,  PINX1p,  hPINX1,  E5RGR1,  E5RJG9 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence

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