Subcellular localization database

RNF135 localizations

RNF135 [ENSP00000328340]

RING-type E3 ubiquitin transferase RNF135; Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production; Ring finger proteins

Synonyms:  RNF135,  RNF135p,  hRNF135,  B3KV69,  H7C3H8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence