Subcellular localization database

APCDD1 localizations

APCDD1 [ENSP00000347433]

Adenomatosis polyposis coli down-regulated 1 protein; Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis; Belongs to the APCDD1 family.

Synonyms:  APCDD1,  APCDD1p,  hAPCDD1,  J3KTQ6,  J3KTR1 ...

Linkouts:  STRING  Pharos  UniProt #1 #2  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence