Rho guanine nucleotide exchange factor (GEF) 26; Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry; Pleckstrin homology domain containing
Synonyms: ARHGEF26, Q96DR7, HMFN1864, Q96DR7p, hQ96DR7 ...