COMPARTMENTS

Subcellular localization database

ARHGEF26 localizations

ARHGEF26 [ENSP00000348828]

Rho guanine nucleotide exchange factor (GEF) 26; Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry; Pleckstrin homology domain containing

Synonyms:  ARHGEF26,  Q96DR7,  HMFN1864,  Q96DR7p,  hQ96DR7 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence