TRIM38 localizations
TRIM38 [ENSP00000349596]
E3 ubiquitin-protein ligase TRIM38; E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
Synonyms: TRIM38, TRIM38p, hTRIM38, A0A024QZY4, O00635 ...
Linkouts: STRING Pharos UniProt
Knowledge
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| Name | Source | Evidence | Confidence |
|---|---|---|---|
| Tight junction | UniProtKB | IDA | ★★★★★ |
| Plasma membrane | HPA | IDA | ★★★★☆ |
| Cell junction | HPA | IDA | ★★★★☆ |
| Extracellular exosome | UniProtKB | HDA | ★★★★☆ |
| Low-density lipoprotein particle | UniProtKB-KW | IEA | ★★★☆☆ |
| Chylomicron | UniProtKB-KW | IEA | ★★★☆☆ |
| Tricellular tight junction | ARUK-UCL | ISS | ★★★☆☆ |
| Very-low-density lipoprotein particle | UniProtKB-KW | IEA | ★★★☆☆ |
| Bicellular tight junction | UniProtKB-SubCell | IEA | ★★★☆☆ |
| Bicellular tight junction | UniProtKB-SubCell | IEA | ★★★☆☆ |
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Predictions
| Name | Source | Evidence | Confidence |
|---|---|---|---|
| Nucleus | PSORT | 11/32 | ★★☆☆☆ |
| Cytosol | PSORT | 10/32 | ★☆☆☆☆ |
| Plasma membrane | YLoc | 51.8% | ★☆☆☆☆ |
| Peroxisome | YLoc | 41.6% | ★☆☆☆☆ |
| Endoplasmic reticulum | PSORT | 3/32 | ★☆☆☆☆ |
| Peroxisome | PSORT | 3/32 | ★☆☆☆☆ |
| Mitochondrion | PSORT | 3/32 | ★☆☆☆☆ |