COMPARTMENTS

Subcellular localization database

JensenLab

TRIM38 localizations

TRIM38 [ENSP00000349596]

E3 ubiquitin-protein ligase TRIM38; E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.

Synonyms:  TRIM38,  TRIM38p,  hTRIM38,  A0A024QZY4,  O00635 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
Knowledge
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NameSourceEvidenceConfidence
Tight junctionUniProtKBIDA★★★★★
Plasma membraneHPAIDA★★★★☆
Cell junctionHPAIDA★★★★☆
Extracellular exosomeUniProtKBHDA★★★★☆
Low-density lipoprotein particleUniProtKB-KWIEA★★★☆☆
ChylomicronUniProtKB-KWIEA★★★☆☆
Tricellular tight junctionARUK-UCLISS★★★☆☆
Very-low-density lipoprotein particleUniProtKB-KWIEA★★★☆☆
Bicellular tight junctionUniProtKB-SubCellIEA★★★☆☆
Bicellular tight junctionUniProtKB-SubCellIEA★★★☆☆

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Predictions
NameSourceEvidenceConfidence
NucleusPSORT11/32★★☆☆☆
CytosolPSORT10/32★☆☆☆☆
Plasma membraneYLoc51.8%★☆☆☆☆
PeroxisomeYLoc41.6%★☆☆☆☆
Endoplasmic reticulumPSORT3/32★☆☆☆☆
PeroxisomePSORT3/32★☆☆☆☆
MitochondrionPSORT3/32★☆☆☆☆