COMPARTMENTS

Subcellular localization database

PCBP2 localizations

PCBP2 [ENSP00000352438]

Heterogeneous nuclear ribonucleoprotein E2; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation.

Synonyms:  PCBP2,  PCBP2p,  hPCBP2,  B4DRD7,  B4DXP5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence