HIST1H2AM localizations
HIST1H2AM [ENSP00000352627]
Histone cluster 1, H2am; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: HIST1H2AM, 4QYL, 5KGF, 8329, 8330 ...