UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region; Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Synonyms: GALNT2, GALNT2p, hGALNT2, Q10471, Q10471p ...