COMPARTMENTS

Subcellular localization database

DSTYK localizations

DSTYK [ENSP00000356130]

Receptor-interacting serine/threonine-protein kinase 5; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.

Synonyms:  DSTYK,  Q6XUX3,  HDCMD38P,  KIAA0472,  Q6XUX3p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence