COMPARTMENTS

Subcellular localization database

GBP5 localizations

GBP5 [ENSP00000359488]

Guanine nucleotide-binding protein 5; As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents. Hydrolyzes GTP, but in contrast to other family members, does not produce GMP.

Synonyms:  GBP5,  GBP5p,  hGBP5,  E7ETN8,  FLJ00401 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence