COMPARTMENTS

Subcellular localization database

AGO4 localizations

AGO4 [ENSP00000362306]

Eukaryotic translation initiation factor 2C 4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV); Belongs to the argonaute family. Ago subfamily.

Synonyms:  AGO4,  AGO4p,  hAGO4,  Q9HCK5,  Q9NXV9 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence