COMPARTMENTS

Subcellular localization database

TSPAN15 localizations

TSPAN15 [ENSP00000362387]

Transmembrane 4 superfamily member 15; Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity; Belongs to the tetraspanin (TM4SF) family.

Synonyms:  TSPAN15,  TSPAN15p,  hTSPAN15,  H7C285,  O95858 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence