COMPARTMENTS

Subcellular localization database

ATP6V1G1 localizations

ATP6V1G1 [ENSP00000363162]

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.

Synonyms:  ATP6V1G1,  A0A024R883,  O75348,  ATP6G,  ATP6G1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence