COMPARTMENTS

Subcellular localization database

PRDX4 localizations

PRDX4 [ENSP00000368646]

Thioredoxin-dependent peroxide reductase A0372; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I- kappa-B-alpha phosphorylation; Peroxiredoxins

Synonyms:  PRDX4,  PRDX4p,  hPRDX4,  A6NG45,  A6NJJ0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence