COMPARTMENTS

Subcellular localization database

LILRB4 localizations

LILRB4 [ENSP00000375616]

Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5- signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions; CD molecules

Synonyms:  LILRB4,  LILRB4p,  hLILRB4,  Q8NHJ6,  ILT3 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence