Subcellular localization database

PNLDC1 localizations

PNLDC1 [ENSP00000376007]

poly(A)-specific ribonuclease (PARN)-like domain containing 1; 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells (By similarity).

Synonyms:  PNLDC1,  PNLDC1p,  hPNLDC1,  Q8NA58,  V9GYA0 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence