COMPARTMENTS

Subcellular localization database

SLC11A2 localizations

SLC11A2 [ENSP00000378364]

Solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria; Belongs to the NRAMP family.

Synonyms:  SLC11A2,  SLC11A2p,  hSLC11A2,  B3KY44,  F8VR36 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence