COMPARTMENTS

Subcellular localization database

EXT2 localizations

EXT2 [ENSP00000379032]

Putative tumor suppressor protein EXT2; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan.

Synonyms:  EXT2,  EXT2p,  hEXT2,  E9PJA5,  E9PNL9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence